SSRI Use Associated with Birth Defects

Selective Serotonin Reuptake Inhibitors (SSRIs) are types of antidepressants. Brand names of SSRIs include: Paxil, Zoloft, Celexa, Prozac, Lexapro, Symbyax, Wellbutrin and Effexor. These drugs inhibit neuronal serotonin and norepinephrine reuptake and slightly inhibit dopamine reuptake. SSRIs have been associated with serious, life-threatening birth defects.

Research suggests that, if a mother took SSRI’s during pregnancy, the infant could be at increased risk of the following:

• Heart defects

• Persistent Pulmonary Hypertension of a Newborn (PPHN)

• Lung defects

• Brain and spinal cord defects

• Abdominal wall defects

• Limb defects, and

• Congenital abnormalities

On December 14, 2011, the U.S. Food and Drug Administration issued a safety announcement advising the public that there are conflicting findings from new studies evaluation this potential risk, making it unclear whether use of SSRIs during pregnancy can cause Persistent Pulmonary Hypertension of a Newborn (PPHN). 12.14.2011 FDA Safety Announcement

If you took an antidepressant during pregnancy and your child suffered any of the birth defects that are identified, we would like to speak with you to determine if those defects were caused by your medication. There is no obligation to you and the inquiry is free.

Please email Attorney John Evans at or give him a call at 1-800-642-5297.

You may also complete the short form below or call us at 1-800-642-5297 for a free, confidential consultation at a time convenient for you.

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